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Molecular & Cell Biology

The Giardina Laboratory

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The Giardina Laboratory
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Charlie Giardina and his students Anton Kuratnik and Avi Chopra (left to right) planning experiments in the labSome of the past members of the Giardina labDrug discovery through in silico modellingCao et al. Development of intestinal organoids as tissue surrogates: Cell composition and epigenetic control of differentiation.From left to right: Brian Aneskievich, Charles Giardina, Joerg Graf, Lawrence HightowerPresentation on the regulation of Cox-2 activation in colon cancer cells.

Research overview

My laboratory studies the inter- and intra-cellular signaling events required for maintaining the structure and function of intestinal epithelium, with a focus on those events involved in epithelial cell proliferation and death.
 
We are also trying to understand the molecular mechanisms of transcription factor regulation by chemical and physical injury.

Upcoming events

  1. Oct 29 MCB Cell Biology Journal Club12:30pm

    MCB Cell Biology Journal Club

    Thursday, October 29th, 2020

    12:30 PM - 01:30 PM

    Storrs Campus
    online

    MCB Cell Biology Journal Club
    This week in Cell Biology Journal Club, Michael Griffith will lead a discussion of "Cargo adaptors regulate stepping and force generation of mammalian dynein–dynactin” by Elshenawy et al., 2019.
    https://mcb.uconn.edu/wp-content/uploads/sites/2341/2020/10/Elshenawy-et-al-2019.pdf

    Please feel free to join us online, Thursday, 12:30-1:30pm, on Blackboard Collaborate:

    https://us.bbcollab.com/guest/5eb9178779e24c38852733f8fb6415e8

    Contact Information: david.daggett@uconn,edu

    More
  2. Oct 29 EEB Seminar: Gustavo Londoño3:30pm

    EEB Seminar: Gustavo Londoño

    Thursday, October 29th, 2020

    03:30 PM - 04:30 PM

    Storrs Campus
    online

    EEB Seminar: Gustavo Londoño
    Life history and physiological diversification in the Andean mountains.

    (Email contact for zoom link.)

    Contact Information: Carlos Garcia-Robledo

    More
  3. Oct 29 MCB PSM Professional Development Seminar5:00pm

    MCB PSM Professional Development Seminar

    Thursday, October 29th, 2020

    05:00 PM - 06:00 PM

    Storrs Campus
    Virtual

    MCB PSM Professional Development Seminar
    Jeff Heinzman
    Clinical Trial Manager, Altasciences

    * Attendance is limited to MCB PSM, PM, and Ph.D. students

    Contact Information: elaine.mirkin@uconn.edu

    More
  4. Oct 30 MCB Research Seminar: Grady and Haarer12:20pm

    MCB Research Seminar: Grady and Haarer

    Friday, October 30th, 2020

    12:20 PM - 01:00 PM

    Other
    Online

    MCB Research Seminar: Grady and Haarer
    MCB Research Seminar

    Patrick Grady, R. O'Neill Lab

    “Do wallabies drive? Examining hypotheses of centromere and CENP co-evolution in macropods”

    Elena Haarer, Campellone Lab

    “Linking the Actin Cytoskeleton to Genomic Integrity and Cell Senescence”

    Seminar Link: https://us.bbcollab.com/collab/ui/session/guest/0453116de50844fe86f3edee5f7c6cc4

    Contact Information: victoria.robinson@uconn.edu

    More

Lab news

  • Cancer Prevention Research Publication
  • Biosynthesis course Fall 2015
  • Cell Stress and Chaperones publication
  • Publication in Biochemical Pharmacology
Last updated: April 17, 2015
© Charles Giardina, 2015
Created by: Avijeet Chopra
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